What is Qsymia?

Qsymia is the only once daily FDA approved diet pill for long term weight loss. It is unique because it is the first weight loss drug to be approved by FDA in over 15 years due its unique synergistic effect.

It is a unique combination of two well known drugs, phentermine and topiramate, but new formulation.

The main difference is “summation of effect without summation of side effects.”

For that reason at Allergy and weight Loss center and Concord weight loss center we use Qsymia for short and long term weight loss

Qsymia FDA Approved Drug

Qsymia FDA Approved Drug

Qsymia or Qnexa?

Qsymia had been known as Qnexa until its approval. The FDA asked the company to change the name to avoid confusion with another drug on the market, according to the company.

How does Qsymia work?

Phentermine is appetite suppressant. Topiramate acts on the brain neurotransmitters. This medication acts on serotonin , a neurotransmitter that has been implicated
in depression

Phentermine is an appetite suppressant. It triggers the release of norepinephrine in the brain, which increases blood concentrations of leptin, an appetite-regulating hormone.

Topiramate, commonly known as Topamax, is prescribed as an anticonvulsant and migraine medication. It can aid in weight loss by increasing the feeling of being full, making foods taste less appealing and increasing calorie expenditure.

Read more: http://www.foxnews.com/health/2012/07/25/all-need-to-know-about-qsymia/#ixzz2N1Ta1wLX

Qsymia indications

Qsymia is indicated for weight loss if
1. If your BMI is over 30 or
2. If your BMI is more than 27 with medical problems such as hypertension, diabetes, high cholesterol, sleep apnea, heart disease, stroke, PCOS etc.

  • Must NOT be pregnant, trying to get pregnant, or unable/unwilling to comply with contraceptive guidance
  • No glaucoma
  • No hyperthyroidism
  • Not using monoamine oxidase inhibitors (MAOIs) or have not used within 14 days
  • No known hypersensitivity or idiosyncrasy to the sympathomimetic amines

How can you get Qsymia?

  • Qsymia is Class IV controlled  drug.
  • Qualified medical doctor faxes the prescription to central pharmacies like Walgreen, Express Scripts, or CVS
  • Medication is shipped to your home address directly
  • The first order includes two weeks starter dose, and one additional month’s supply
  • Qsymia cannot be filled by local pharmacy or by any online pharmacy.

What doses of Qsymia available?

Qsymia is available as phentermine hydrochloride (as the free base)/topiramate extended-release gelatin capsules in the following strengths and colors:


  • 3.75 mg/23 mg [Purple cap imprinted with VIVUS, Purple body imprinted with 3.75/23]
  • 7.5 mg/46 mg [Purple cap imprinted with VIVUS, Yellow body imprinted with 7.5/46]
  • 11.25 mg/69 mg [Yellow cap imprinted with VIVUS, Yellow body imprinted with 11.25/69]
  • 15 mg/92 mg [Yellow cap imprinted with VIVUS, White body imprinted with 15/92]

Side effects of Qsymia

  • Qsymia side effects are much less than the individual components of phentermine and topiramate because Dose of phentermine is much less than usually used in weight loss clinics
  • Top dose in Qsymia is 15 mg of phentermine as opposed to 37.5 mg Dose of topiramate is much less than used for migraine prevention ro seizure disorder.
  • Top dose in Qsymia is 92mg as opposed to 300-400mg Combination of the drugs cancel out the upper/downer side effects

Qysymia starting dose

Qsymia™ is initiated with a starting dose of 3.75 mg/23 mg† that is increased after 14 days of treatment to a recommended dose of 7.5 mg/46 mg. After 30 days on this dose, the patient should be evaluated and the dose titrated based on response.

To begin, your doctor will write 2 prescriptions:

  • 14 days on starting dose (3.75 mg/23 mg)
  • 30 days on recommended dose (7.5 mg/46 mg)
  • Once daily, in the morning, with or without food

Qsymia dose titration

After 12 weeks at recommended dose of 7.5 mg/46 mg

  • If weight loss is less than 3%, discontinue Qsymia or escalate the dose
  • To escalate dose, prescribe:
    • 14 days on titration dose of 11.25 mg/69 mg
    • 30 days on top dose of 15 mg/92 mg

After additional 12 weeks following dose escalation to top dose of 15 mg/92 mg

  • If weight loss is less than 5% after 12 weeks, discontinue treatment
  • Discontinue top dose (15 mg/92 mg) gradually by taking a dose every other day for at least 1 week prior to stopping altogether, due to the possibility of precipitating a seizure with abrupt cessation of the drug

Qsymia information resources