Leaky Gut Syndrome

What is leaky gut syndrome?

Leaky Gut Syndrome

Graphic From: www.leakygutcure.com

The term Leaky Gut Syndrome is used to describe the condition of increased intestinal permeability. The intestinal lining has became more porous, with more holes developing that are larger in size and the filtering out process is no longer functioning properly. The leaky gut leads to undigested food molecules, yeast, toxins, and all other chemicals that your body normally doesn’t allow through, to flow freely into your bloodstream.

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What causes Leaky gut?

  • Foods high in the glycemic index, high sugar
  • Foods high in refined flours, processed foods with low fiber contents (Amylose high foods)
  • Foods high in caffeine that are chronically used.
  • Excessive use of alcohol
  • Long term use or abuse of antibiotics.
  • Chronic use of drugs like aspirin or ibuprofen (NSAIDs)
  • Proton pump inhibitors
  • Foods with wrong cooking oil e.g omega 6 oils, trans fats
  • Food allergy
  • Zinc defiency
  • Inflammatory bowel disease.

How leaky gut leads to symptoms?

Any undigested foods that are absorbed into the blood stream are now considered enemies, and your immune system will develop reactions to many of them, leading to food intolerances. When you have a Leaky Gut condition, the damaged microvilli along the intestinal lining cannot make the digestive enzymes they need to break down the food. The resulting condition allows food molecules to flow into the bloodstream that have not been completely broken down into the nutrients your body needs. Some of these food particles and cytokines travel across the blood brain barrier and cause brain fog, confustion, insomnia, mood disorders etc.

Leaky gut and GALT

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What are symptoms of leaky gut syndrome?

  • Abdominal pain (chronic), bloating, excessive flatulance, heart burn, constant hunger pains, constipation or diarrhea, hemorroids, anal irritation
  • Brain fog, insomnia, anxiety, migraine, mood swings, depression, poor memory, chronic fatigue,
  • Muscle cramps, muscle pain, joint pain,
  • Multiple chemical sensitivities
  • Poor exercise tolerance, shortness of breath
  • Recurrent bladder infections, recurrent vaginal infections, recurrent sinusitis
  • Recurrent skin rashes, brittle nails, hair loss
  • Swollen lympth glands
  • The passage of certain gut antigens has been associated with autoimmune disorders like rehumatoid arthritis, akylosing spondylitis, Hashimotos thyroiditis and myasthenea gravis.

Malabsoption syndrome Vs Leaky guty Syndrome

Malabsorption means nutrients are not being absorbed properly. You might have leaky gut involved, but you can also have malabsorption without leaky gut. If you have a pancreatic problems, poor stomach acid, various chronic diseases, surgical removal of part of your intestine (e.g. for weight loss surgery), you might have an intact gut lining but for some reason, some nutrients are not being absorbed properly. This might be many nutrients or only a few in particular.

How is leaky gut diagnosed?

At allergy and weight loss clinic, we use Genova Diagnostics intestinal permeability test to diagnose leaky gut syndrome. Because it is a main stream medical diagnostic test, your health insurance may cover the test.
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What does intestinal permealbity test involve?

Following an overnight fast, the patient collects a urine sample and then drinks a premeasured challenge drink containing lactulose and mannitol (two nonmetabolized sugar molecules). A second urine sample is later drawn from a six-hour collection.

The report includes lactulose percent recovery, mannitol percent recovery and a lactulose/mannitol ratio.

Treatment of leaky gut syndrome

Healing leaky gut needs

digestive enzymes
oats/oatmeal (see study below)
Because enzymes can process the food particles down to their essential forms, anything that does leak through the gut while it is healing is less likely to provoke a negative reaction.

Proteases are the important enzymes. Another benefit of taking proteases between meals is to reduce inflammation. Bromelain and papain (protease enzymes derived from pineapple and papaya) have undergone study in great detail for this purpose and are found to be incredibly effective at reducing inflammation.

The nice thing about enzymes is they address the damaged gut, problematic peptides, food intolerances, and nutrient deficiencies all at the same time.






A good probiotic will help restore the needed balance among the bacteria, yeast, and other microorganisms. Out with the bad and in with the good. A consistent supply of probiotics is like tending a lawn. You need to kill the weeds, and then keep seeding with the ‘good’ grasses. A healthy lawn will need just a little maintenance. However, doing no maintenance will very soon give you a yard overrun with weeds.